.1B Bet on Autoimmune T Cell Engager | FieldPulse

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Gilead Moves Beyond HIV with $2.1B Bet on Autoimmune T Cell Engager

By FieldPulse Editorial · March 24, 2026

Tags: Mergers & Acquisitions, Immunology, Pipeline

Gilead Sciences is acquiring Ouro Medicines for $2.1 billion to gain OM336, a first-in-class BCMAxCD3 T cell engager being developed for autoimmune diseases, signaling the company's intent to expand well beyond its HIV stronghold.

Gilead Sciences announced Monday it will acquire Ouro Medicines for $2.1 billion, securing rights to OM336 — also known as gamgertamig — a novel BCMAxCD3 T cell engager being developed for autoimmune diseases. The transaction marks a deliberate push by Gilead to diversify its revenue base beyond HIV, where it has long dominated but where growth headroom is increasingly constrained. OM336 works by engaging T cells to target BCMA-expressing cells implicated in autoimmune pathology — a mechanism more commonly associated with oncology applications, specifically multiple myeloma, now being explored